See the following:
U44M1P7 - Updates :
http://helpx.adobe.com/creative-suite/kb/error-u44m1p7-installing-upda tes-ccm.html
U44M1P7, U44M2P7 - Creative Cloud Help / Can't apply Extension Manager update 6.0.2 | Mac OS :
http://helpx.adobe.com/creative-suite/kb/unable-apply-extension-manage r-update.html