I too have a problem updating apps using the Adobe Update Manager. For me, all updates work sucessfully, except for Premiere Pro and Illustrator. I just ran Adobe Update manager a few minutes ago and it updated its-self first, and sucessfully applied updates for heaps of things, except for these 2.
I downloaded the latest updates for those from the Adobe update website, and confirmed that the updates were applies sucessfully, however Adobe Update Manager insists those 2 programs need to be updated to the version that they are already updated to, and, naturally, fails to update them when reaching 100% progress during the update.
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In this case, i bet any money that when a newer update is available for them than the 1 i applied manually, it will work properly from thereon. Although all my apps are up to date, Its still annoying that Adobe Update Manager fails to decect that 2 of them were updated manually already using the official adobe update patches.